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PACHYDERMOPERIOSTOSIS

AN UNUSUAL CAUSE OF FINGER CLUBBING

J. H. LAZARUS M.A., M.B., M.R.C.P.1 and J. K. GALLOWAY M.B., CH.B., D.M.R.D.

1 Department of Medicine, Welsh National School of Medicine, Heath, Cardiff, Wales.

A case of pachydermoperiostosis (idiopathic hypertrophic osteoarthropathy), is described in a 38 year old male.

The diagnosis was made roentgenologically by noting the presence of periosteal new bone formation in the shafts of the tibia, fibula, radius and ulna and to a lesser extent in the metacarpals, metatarsals and phalanges of the hands and feet; there was associated clubbing in the absence of any clinical cause.

Acromegaly was excluded by the presence of normal values of plasma growth hormone and the hypothalamic pituitary axis was intact.

It is suggested that the etiology is not related to endocrine factors.

The prognosis is discussed.


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