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SERIAL SCINTIGRAMS IN THE COURSE OF ECTOPIC BONE FORMATION IN PARAPLEGIC PATIENTS

GEORGES MUHEIM M.D.1, ALFRED DONATH M.D.2, and ALAIN B. ROSSIER M.D.3

1 Division of Orthopaedics, Department of Surgery.
2 Chief of Division of Nuclear Medicine, Department of Internal Medicine, Professor of Nuclear Medicine.
3 Chief of Spinal Cord Injury Center, Institute of Physical Medicine and Rehabilitation.

The course of ectopic bone formation in paraplegic patients was investigated by serial Sr85 or Sr87m scintigrams.

Differences in uptake on consecutive scintigrams in the same patient were expressed by means of an uptake ratio between ectopic and normal bone.

In most cases the uptake ratios tended to decrease with time.

Surgical removal of ectopic bone, when indicated, was not followed by recurrence.

In some rare cases, however, strontium uptake remained high over several years and the uptake ratios increased. In these cases removal of ectopic bone was followed by recurrence.


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D. Shehab, A. H. Elgazzar, and B. D. Collier
Heterotopic Ossification
J. Nucl. Med., March 1, 2002; 43(3): 346 - 353.
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