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RAPID AFTERLOADING WITH GUIDE FIXATION OF RADIOACTIVE SOURCES IN CANCER OF THE ORAL CAVITY

T. SHARETT M.D.1, L. FINE B.D.S.2, and T. C. CHIANG M.D.3

1 Fellow of the American Cancer Society, Department of Radiology, University of Chicago.; Associated Radiologists, 1010 Park Avenue, Plainfield, New jersey 070(0.
2 Zoller Dental Clinic, University of Chicago.
3 Department of Radiology, Veterans' General Hospital, VACRS, Taipei, Taiwan, 112, Republic of China; Formerly the Argonne Cancer Research Hospital.

A new technique of rapid afterloading with guide fixation and removal of radioactive sources for interstitial gamma-ray therapy in cancers of the oral cavity was applied in a single case. The guide is a custom mold constructed to fit the patient’s own anatomic configuration, and is fixed in position for treatment by being anchored to the teeth of the lower mandible. Consequently, the sources are also fixed in the geometry necessary to achieve homogeneity of irradiation throughout the tumor volume.

Previously, radioactive sources have been placed without fixed guides, or have been anchored to soft tissue; this led to distortions of geometry and resulted in under- or overdosing of the tumor and normal tissue.

The present procedure is harmless to the patient.

We recommend further trials for candidates with suitably accessible lesions where guide fixation to a nearby rigid anatomic structure is possible.


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