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VALUE OF RADIATION THERAPY IN THE TREATMENT OF ORBITAL METASTASIS

SUN H. HUH M.D., LOURDES Z. NISCE M.D., LARRY D. SIMPSON PH.D., and FLORENCE C. H. CHU M.D.

A series of 70 cases of extraocular orbital metastases treated by radiation therapy was reviewed. Carcinoma of the breast and lymphoma were the most common types. Most metastatic lesions occurred in the orbital cavity, particularly in the retrobulbar region. There were 9 cases of bilateral involvement. The clinical manifestations of these patients are described.

Radiation therapy was effective in producing worthwhile palliation. Of the 79 lesions treated, 39 per cent showed marked improvement for an average duration of 17 months, 33 per cent showed slight improvement for a duration of 7 months and 28 per cent failed to respond.

The planning of radiation therapy should be individualized according to the location and extent of tumor involvement. The tumor dose recommended is 2,000-3,000 rad delivered in about 2 weeks for lymphoma, and 3,500-4,000 rad delivered in about 3 weeks for breast carcinoma and other types of cancer.


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