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MEGACALYCES: FURTHER OBSERVATIONS AND DIFFERENTIATION FROM OBSTRUCTIVE RENAL DISEASE

LEE B. TALNER M.D. and RUBEN F. GITTES M.D.

Megacalyces is a nonobstructive enlargement of the calyces due to a malformation of the renal papillae. The renal cortex is normal but the medulla is hypoplastic, leading to a variable concentrating defect.

Calyceal urinary stasis predisposes to stone formation and/or infection.

The dilated calyces and reduced parenchymal thickness may resemble obstructive hydronephrosis or postobstructive atrophy, but the urographic and angiographic features of megacalyces are sufficiently distinctive for the correct diagnosis to be suggested in most cases.

Renal function tests and radioisotope studies are important in substantiating the diagnosis.


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