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PULMONARY INVOLVEMENT IN ADULTS WITH CYSTIC FIBROSIS

EMANUEL E. SCHWARTZ M.D. and DOUGLAS S. HOLSCLAW M.D.

Cystic fibrosis is no longer rare in adults. The lung is the main target organ and the basic lesion is bronchial obstruction leading to bronchiectasis. Interstitial infiltrates and cyst-like changes are characteristic on roentgenography.

Complications include pulmonary hypertension, pneumonitis, hemorrhage, and pneumothorax.

Little correlation exists between respiratory tract and pancreatic and gastrointestinal involvement, despite similarities in pathogenesis.

Pulmonary cystic fibrosis in adults does not always resemble the condition in children, and must be differentiated from other chronic interstitial diseases.*


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