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CHILDHOOD RHABDOMYOSARCOMA

ANALYSIS OF COORDINATED THERAPY AND RESULTS

CARLOS H. FERNANDEZ M.D.1, WATARU W. SUTOW M.D.2, ORLANDO R. MERINO M.D.3, and STEPHEN L. GEORGE PH.D.4

1 Assistant Radiotherapist and Assistant Professor of Radiotherapy, The University of Texas System Cancer Center, M.D. Anderson Hospital and Tumor Institute, Houston, Texas.
2 Pediatrician and Professor of Pediatrics, The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas.
3 Fellow in Radiotherapy, The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas.
4 Assistant Biometrician and Assistant Professor of Biometrics, The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas.

The current utilization of an intensive coordinated therapy program (surgery, radiotherapy, and intensive multidrug chemotherapy) has increased the success rate in treatment for rhabdomyosarcoma in children. A 68 per cent 3 year survival and 89 per cent local control of rhabdomyosarcoma of head and neck substantiate this.

These results suggest that surgical procedures regarding rhabdomyosarcoma primary in other sites require re-evaluation and possible modification.


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