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PSEUDO-MALIGNANT LESIONS IN PAGET’S DISEASE OF BONE

JACK W. BOWERMAN M.D.1, JEREMY ALTMAN M.D.2, JAMES L. HUGHES M.D.3, and ROBERT E. ZADEK M.D.3

1 Assistant Professor in Radiology.
2 Instructor in Radiology.
3 Assistant Professor in Orthopedic Surgery.

Two patients with unusual features of Paget’s disease are reported.

In one patient a circumferential focal and periosteally based mass of Paget’s disease presented as a mass lesion superimposed on the sclerotic phase of Paget’s disease in the distal femur. Biopsy of the mass showed Paget’s disease without neoplasia. The mass has remained unchanged roentgenographically in a 2 year period.

In a second patient, a lesion occurred in the mid-portion of the tibia and showed features of the early and radiolucent phase of Paget’s disease.

In a 4 year period, the lesion has progressed to a more sclerotic phase and to occupy the proximal end of the tibia as well as its mid and lower portions.


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