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MINIMAL DEVIATION HEPATOMA

A NEW ENTITY

SHELBY J. GALLOWAY M.D., WILLIAM J. CASARELLA M.D., RAFFAELE LATTES M.D., and WILLIAM B. SEAMAN M.D.

The term minimal deviation hepatoma has been applied to a specific clinical, pathological, and angiographic entity. It is a tumor, composed of atypical cells, which is neither frankly malignant nor so well organized as a benign tumor. This lesion occurs in females with otherwise normal livers and has a relatively benign course, although life threatening hemorrhage may occur. The diagnosis may be strongly suggested in the presence of hypervascular or hypovascular discrete masses without evidence of frank malignancy, with a defect in the colloid liver scan and with normal liver function tests. Surgical resection when possible and aggressive chemotherapy may be corrective in many cases.


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