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American Journal of Roentgenology, Vol 127, Issue 6, 897-899
Copyright © 1976 by American Roentgen Ray Society

Articles

ARS Presidential Address: Estrogen therapy: a causal role in endometrial cancer?

FN Rutledge

Publicity associated with recent reports of a greater frequency of adenocarcinoma of the endometrium among women who take exogenous estrogens has created confusion among physicians and fear among patients. An objective review of available data on estrogen effects and current epidemiologic evidence suggests that estrogen may play an indirect role in the development of endometrial carcinoma. Until definitive data are available, physicians should exercise caution in prescribing estrogens, monitoring the status of the endometrium at regular intervals by sampling and pathologic analysis.
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Copyright © 1976 by the American Roentgen Ray Society.