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American Journal of Roentgenology, Vol 128, Issue 4, 599-600
Copyright © 1977 by American Roentgen Ray Society

Articles

Vertebral end-plate depression: report of two patients without hemoglobinopathy

BM Rohlfing

Center vertebral end-plate depression was originally reported to be pathognomonic for sickle cell disease. Two patients without hemoglobinopathy were found to have this deformity. One patient has congenital hereditary spherocytosis; the other has no blood dyscrasia but is osteopenic. Therefore, although this deformity is usually due to sickle cell disease, it is not pathognomonic.
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Copyright © 1977 by the American Roentgen Ray Society.