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American Journal of Roentgenology, Vol 131, Issue 1, 129-132
Copyright © 1978 by American Roentgen Ray Society

Articles

Comparison of arachnoiditis produced by meglumine iocarmate and metrizamide myelography in an animal model

VM Haughton, KC Ho, SJ Larson, GF Unger, and F Correa-Paz

Myelography in monkeys was performed with either meglumine iocarmate or metrizamide. The severity of resultant arachnoiditis in each animal 12 weeks later was evaluated by repeat myelography and by histologic study of the arachnoid. Three of the four animals examined with meglumine iocarmate had severe arachnoiditis; none of the four animals examined with metrizamide had as severe changes. The difference between the two groups was statistically significant (P less than .05).
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Copyright © 1978 by the American Roentgen Ray Society.