American Journal of Roentgenology, Vol 133, Issue 4, 699-702
Copyright © 1979 by American Roentgen Ray Society
Osteogenic sarcoma after retinoblastoma radiotherapy
JJ Pagani,
LW Bassett,
J Winter,
RH Gold,
and
M Brawer
Development of osteogenic sarcoma after retinoblastoma radiotherapy in three patients, two of whom were siblings, is reported. Pluridirectional tomography and plain skull radiography demonstrated soft tissue masses, sinus opacification, and bone destruction and sclerosis in all three patients. Computed tomography reliably indicated the presence or absence of intracranial tumor extension in the two patients in whom it was performed. Radionuclide bone scanning was a useful adjunct for osteosarcomatous detection.