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The development of a widened mediastinum in patients with neoplastic disease frequently indicates tumor recurrence or spread. Seven cases of mediastinal widening in children with a variety of neoplasms are described wherein the etiology is either proven or strongly suspected to be benign thymic enlargement. Awareness of this benign etiology for mediastinal widening may avert a diagnostic surgical procedure. A steroid trial in certain specific cases may assist in differentiating benign from malignant etiologies.
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M. B. C C. Neto, M. C. Machado, F. Mesquita, N. R. de Castro Musolino, A. C. Toscanini, G. Ochman, V. A. S Cescato, R. Marino Jr, and M. J. Teixeira Thymus hyperplasia after resolution of hypercortisolism in ACTH-dependent Cushing's syndrome: the importance of thymic vein catheterization. Eur. J. Endocrinol., June 1, 2006; 154(6): 807 - 811. [Abstract] [Full Text] [PDF] |
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G. Jerusalem, Y. Beguin, M. F. Fassotte, T. Belhocine, R. Hustinx, P. Rigo, and G. Fillet Early detection of relapse by whole-body positron emission tomography in the follow-up of patients with Hodgkin's disease Ann. Onc., January 1, 2003; 14(1): 123 - 130. [Abstract] [Full Text] [PDF] |
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