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American Journal of Roentgenology, Vol 138, Issue 5, 917-920
Copyright © 1982 by American Roentgen Ray Society

Articles

Contrast extravasation through Dacron grafts: a sequela of low-dose streptokinase therapy

FE Rabe, GJ Becker, BD Richmond, HY Yune, RW Holden, RS Dilley, and EC Klatte

Local transcatheter administration of low-dose streptokinase for the treatment of thrombosed Dacron grafts was performed in four patients. Angiography after the infusion revealed extravasation of contrast material through the interstices of the graft. In each case the graft material was knitted Dacron, Surgically placed 1 month to 6 years before infusion with streptokinase. The fibrinolytic activity of streptokinase is likely responsible for lysis of the fibrin in the interstices of the graft with resultant extravasation of contrast material.
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