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American Journal of Roentgenology, Vol 141, Issue 1, 151-156
Copyright © 1983 by American Roentgen Ray Society

Articles

Perfusion of nonventilated lung: failure of hypoxic vasoconstriction?

HD Sostman, RD Neumann, A Gottschalk, and RH Greenspan

Alveolar hypoxia is a well established cause of regional vasoconstriction such that nonventilated segments are not perfused. The paradoxical situation of retained perfusion of nonventilated lung has seldom been discussed. Three clinical examples are illustrated. In each case coexistent chronic obstructive lung disease may have contributed to this unexpected finding by reducing pulmonary vascular capacity such that blood flow diversion from hypoxic segments was not possible.
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