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Magnetic resonance imaging (MRI) has been shown to be far more sensitive than computed tomography (CT) in the detection of multiple sclerosis plaques within the brain. Unlike CT, MRI is also able to detect multiple sclerosis in the brainstem and cerebellum. This report is the first description of MRI of multiple sclerosis plaques within the cervical spinal cord. Twenty-one patients with clinically typical multiple sclerosis had characteristic plaques within the brain. In 10 patients one or more plaques were identified in the cervical spinal cord. Plaques in the spinal cord were detected only in the upper cervical region using the 30-cm head radiofrequency coil. No lesions were identified using the larger-diameter body coil because of poorer signal-to-noise ratio. Further improvement in visualization of plaques in the lower cervical and thoracic spinal cord may depend on development of high-quality surface coils.
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J. C.J. Bot, F. Barkhof, C. H. Polman, G.J. L. a Nijeholt, V. de Groot, E. Bergers, H. J. Ader, and J. A. Castelijns Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination Neurology, January 27, 2004; 62(2): 226 - 233. [Abstract] [Full Text] [PDF] |
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J. C. J. Bot, F. Barkhof, G. L. a Nijeholt, D. van Schaardenburg, A. E. Voskuyl, H. J. Ader, J. A. L. Pijnenburg, C. H. Polman, B. M. J. Uitdehaag, E. G. J. Vermeulen, et al. Differentiation of Multiple Sclerosis from Other Inflammatory Disorders and Cerebrovascular Disease: Value of Spinal MR Imaging Radiology, April 1, 2002; 223(1): 46 - 56. [Abstract] [Full Text] [PDF] |
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