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The authors report three anaphylactic reactions and one allergic reaction during double-contrast studies using glucagon. Symptoms included hives, periorbital edema, and breathing difficulties. Studies performed were three double-contrast barium enemas and one double-contrast upper gastrointestinal series. Glucagon injection and/or an additive in barium suspension are suspected as the likely causes. The allergic potential of glucagon injection, which is not generally appreciated, is reviewed.
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N. Muroi, M. Nishibori, T. Fujii, M. Yamagata, S. Hosoi, N. Nakaya, K. Saeki, and K. Henmi Anaphylaxis from the Carboxymethylcellulose Component of Barium Sulfate Suspension N. Engl. J. Med., October 30, 1997; 337(18): 1275 - 1277. [Full Text] [PDF] |
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