American Journal of Roentgenology, Vol 145, Issue 1, 139-142
Copyright © 1985 by American Roentgen Ray Society
A comparison of Hexabrix and Renografin-60 in knee arthrography
JS Apple,
S Martinez,
MB Khoury,
R Royster,
and
S Allen
Forty patients were randomized in a double-blind study to compare the safety and diagnostic quality of Hexabrix vs. Renografin-60 without epinephrine in knee arthrography. Hexabrix is a monoacidic dimer of meglumine and sodium salts of ioxaglic acid with a lower osmolality than conventional contrast agents of similar concentration (32% iodine). Initial films were of equally high diagnostic quality for both groups, but delayed films at 20 and 30 min significantly favored Hexabrix for diagnostic quality. Hexabrix proved to be a safe and effective contrast agent for knee arthrography.