AJR Your Link to CME
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sanders, C
Right arrow Articles by Fraser, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sanders, C
Right arrow Articles by Fraser, R.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
American Journal of Roentgenology, Vol 149, Issue 5, 881-887
Copyright © 1987 by American Roentgen Ray Society

Articles

Metastatic calcification of the heart and lungs in end-stage renal disease: detection and quantification by dual-energy digital chest radiography

C Sanders, MS Frank, SG Rostand, EA Rutsky, GT Barnes, and RG Fraser

Department of Radiology, University of Alabama, University of Alabama Hospitals, Birmingham 35233.

Metastatic calcification of the lung and heart can cause severe cardiopulmonary compromise and death. Although it is found in most end-stage renal disease patients at autopsy, it is only rarely detected during life. Using a prototype dual-energy digital chest radiographic unit, we measured calcium content (mg/cm2) over the lung and heart in 32 hemodialysis patients. Pulmonary calcium content was significantly greater in these patients than in sex-matched control subjects (men, 230 +/- 43 [mean +/- standard error] vs 166 +/- 7, p less than .05; women, 168 +/- 19 vs 110 +/- 7.5, p less than .001). Abnormal values were detected by dual-energy radiography in 44% of patients (vs 9% of patients studied by conventional radiography). Cardiac calcium content was also significantly greater in the hemodialysis patients than in the control subjects (259 +/- 14 vs 184 +/- 8, p less than .05). Metastatic calcification was significantly correlated with elevated phosphate and calcium-phosphate product levels. Patients with significantly elevated pulmonary calcium content had evidence of restrictive lung disease by functional testing. There was an inverse correlation between elevated cardiac calcium content and ejection fraction. We conclude that dual-energy digital radiography allows premortem diagnosis of metastatic visceral calcification and is more sensitive than current techniques.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 ChestHome page
F. Okada, Y. Ando, S. Yoshitake, A. Ono, S. Tanoue, S. Matsumoto, M. Wakisaka, T. Maeda, and H. Mori
Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax
Chest, December 1, 2007; 132(6): 1939 - 1948.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Radiol.Home page
A Guermazi, H Esperou, F Selimi, and E Gluckman
Imaging of diffuse metastatic and dystrophic pulmonary calcification in children after haematopoietic stem cell transplantation
Br. J. Radiol., August 1, 2005; 78(932): 708 - 713.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
M. Amin, A. Fawzy, M. A. Hamid, and A. Elhendy
Pulmonary Hypertension in Patients With Chronic Renal Failure: Role of Parathyroid Hormone and Pulmonary Artery Calcifications
Chest, December 1, 2003; 124(6): 2093 - 2097.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
T. Stefenelli, C. Abela, H. Frank, J. Koller-Strametz, S. Globits, J. Bergler-Klein, and B. Niederle
Cardiac Abnormalities in Patients with Primary Hyperparathyroidism: Implications for Follow-Up
J. Clin. Endocrinol. Metab., January 1, 1997; 82(1): 106 - 112.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1987 by the American Roentgen Ray Society.