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American Journal of Roentgenology, Vol 155, 153-157, Copyright © 1990 by American Roentgen Ray Society

ARTICLES

Recurrent medulloblastoma: frequency of tumor enhancement on Gd-DTPA MR imaging

N Rollins, D Mendelsohn, A Mulne, R Barton, J Diehl, N Reyes and F Sklar
Department of Radiology, Children's Medical Center, Dallas, TX 75235.

Thirty-two children with medulloblastoma were evaluated postoperatively with conventional and gadolinium-enhanced MR imaging. Eleven patients had abnormal cranial MR studies; nine of these had recurrent tumor. In six patients recurrent tumor enhanced with Gd, while in the other three patients recurrent tumor did not enhance. The remaining two patients had areas of abnormal Gd enhancement that were caused by radiation- induced breakdown of the blood-brain barrier rather than by recurrent tumor. This study shows that not all recurrent medulloblastoma enhances and that the absence of Gd enhancement does not necessarily indicate the absence of recurrent tumor.
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