American Journal of Roentgenology, Vol 157, 693-696, Copyright © 1991 by American Roentgen Ray Society

ARTICLES

Chronic diffuse infiltrative lung disease: comparison of diagnostic accuracy of high-resolution and conventional CT

AN Leung, CA Staples and NL Muller
Department of Radiology, University of British Columbia, Vancouver, Canada.

We compared the accuracies of high-resolution CT (HRCT) and conventional CT in determining the specific diagnoses in 75 consecutive patients with chronic diffuse infiltrative lung disease. Without knowledge of clinical or pathologic data, two reviewers independently assessed three separate sets of CT scans in random order: three HRCT scans, three 10-mm collimation CT scans obtained at the same levels as the HRCT scans, and a complete conventional CT scan. The HRCT scans were obtained at the level of the aortic arch, tracheal carina, and 1 cm above the right hemidiaphragm by using 1.5-mm collimation and a high spatial resolution algorithm. Observers gave the most likely diagnosis along with their degree of diagnostic confidence. The correct diagnosis, irrespective of confidence level, was reached with 71% of the HRCT scans and with 72% of both the corresponding 10-mm and complete conventional CT scans. Confidence level 1 (definite) was reached with 49% of HRCT scans, 31% of corresponding 10-mm scans, and 43% of complete conventional CT examinations; the correct diagnosis was made in 92%, 96%, and 94% of those examinations, respectively. In none of the patients were findings on the limited HRCT scan normal when findings on the conventional CT scan were abnormal. We conclude that in most patients with chronic infiltrative lung disease a specific diagnosis can be made by obtaining a limited number of HRCT scans.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				M. B Gotway, M. M Freemer, and T. E King Jr Challenges in pulmonary fibrosis {middle dot} 1: Use of high resolution CT scanning of the lung for the evaluation of patients with idiopathic interstitial pneumonias Thorax, June 1, 2007; 62(6): 546 - 553. [Abstract] [Full Text] [PDF]

				A. Fukushima, K. Ashizawa, T. Yamaguchi, N. Matsuyama, H. Hayashi, I. Kida, Y. Imafuku, A. Egawa, S. Kimura, K. Nagaoki, et al. Application of an Artificial Neural Network to High-Resolution CT: Usefulness in Differential Diagnosis of Diffuse Lung Disease Am. J. Roentgenol., August 1, 2004; 183(2): 297 - 305. [Abstract] [Full Text] [PDF]

				M. Nishino, M. Kuroki, P. M. Boiselle, J. F. Copeland, V. Raptopoulos, and H. Hatabu Coronal Reformations of Volumetric Expiratory High-Resolution CT of the Lung Am. J. Roentgenol., April 1, 2004; 182(4): 979 - 982. [Abstract] [Full Text] [PDF]

				O. Honda, T. Johkoh, N. Tomiyama, T. Kozuka, N. Mihara, M. Koyama, S. Hamada, H. Naito, H. Nakamura, and M. Kudo High-Resolution CT Using Multidetector CT Equipment: Evaluation of Image Quality in 11 Cadaveric Lungs and a Phantom Am. J. Roentgenol., October 1, 2001; 177(4): 875 - 879. [Abstract] [Full Text] [PDF]

				E. A. Kazerooni High-Resolution CT of the Lungs Am. J. Roentgenol., September 1, 2001; 177(3): 501 - 519. [Full Text] [PDF]

				A. G. Villanueva and E. J. Mark Case 24-1996- A 54-Year-Old Woman with Infiltrative Lung Disease and Mild Dyspnea N. Engl. J. Med., August 8, 1996; 335(6): 417 - 424. [Full Text] [PDF]

				S. E. Weinberger Recent Advances in Pulmonary Medicine- First of Two Parts N. Engl. J. Med., May 13, 1993; 328(19): 1389 - 1397. [Full Text]