American Journal of Roentgenology, Vol 160, 1205-1207, Copyright © 1993 by American Roentgen Ray Society
Sonography in AIDS-related cholangitis: prevalence and cause of an echogenic nodule in the distal end of the common bile duct
F Da Silva, F Boudghene, I Lecomte, Y Delage, JD Grange and JM Bigot
Service de Radiologie, Hopital Tenon, Paris, France.
OBJECTIVE. The purpose of this study was to determine the prevalence and
cause of an echogenic nodule in the distal end of the common bile duct seen
on sonograms in patients who have AIDS-related cholangitis. SUBJECTS AND
METHODS. Sonograms of the liver and bile ducts were obtained in 15 patients
who had AIDS-related cholangitis. Both 3.75- and 5-MHz transducers were
used in all patients. The appearance of an echogenic nodule in the distal
end of the common bile duct was compared with the results of endoscopic
retrograde cholangiograms in 12 patients and with biopsies of the papilla
of Vater in the first five cases. RESULTS. Sonograms showed a hyperechoic
nodule in the distal end of the common bile duct in 10 of the 15 cases.
Visualization was improved after oral administration of water. The finding
correlated with edema of the papilla of Vater noted on retrograde
cholangiograms in eight cases. Biopsy of the papilla of Vater in five cases
showed an inflammatory infiltrate. The nodule became smaller in one patient
when cholestasis improved after treatment for cryptosporidiosis.
CONCLUSION. An echogenic nodule was detected in the distal end of the
common bile duct on sonograms in two thirds of patients who had
AIDS-related cholangitis. Our findings suggest the abnormality is caused by
edema of the papilla of Vater.