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American Journal of Roentgenology, Vol 161, 245-255, Copyright © 1993 by American Roentgen Ray Society

ARTICLES

The dementias: correlation of clinical features, pathophysiology, and neuroradiology

RD Tien, GJ Felsberg, NJ Ferris and AK Osumi
Department of Radiology (Section of Neuroradiology), Duke University Medical Center, Durham, NC 27710.

Current methods of neuroimaging have revolutionized the examination of patients with dementia. Clinical examination of these patients has identified cortical and subcortical patterns of dementia. Each of these patterns can be caused by various diseases. Mixed patterns also occur and also have several possible causes. Neuroimaging can be quite useful in confirming the clinical assessment of the pattern of dementia and in further refining the diagnosis. We review the pathophysiologic basis of and the clinical and neuroimaging findings in dementia, both cortical and subcortical. The roles of neuroimaging in diagnosis, prognostic assessment, and treatment evaluation are discussed.
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Copyright © 1993 by the American Roentgen Ray Society.