AJR Women's Imaging Online
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yetkin, F. Z.
Right arrow Articles by Haughton, V. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yetkin, F. Z.
Right arrow Articles by Haughton, V. M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

American Journal of Roentgenology, Vol 161, 855-858, Copyright © 1993 by American Roentgen Ray Society

ARTICLES

Focal hyperintensities in cerebral white matter on MR images of asymptomatic volunteers: correlation with social and medical histories

FZ Yetkin, ME Fischer, RA Papke and VM Haughton
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, Milwaukee 53226.

OBJECTIVE. Previous attempts to explain the presence of focal hyperintensities in the cerebral white matter on MR images have focused on the patient's age and cardiovascular risk factors. The purpose of this study was to survey many variables in subjects' social, medical, and surgical histories to identify those factors associated with focal hyperintensities in asymptomatic persons. SUBJECTS AND METHODS. Asymptomatic volunteers were examined with MR imaging of the head and questioned concerning smoking history; chemical dependence; alcohol consumption; medical history (e.g., high blood pressure, kidney disease); surgical history (e.g., for appendix, gallbladder); medications (e.g., antihypertensives, analgesics); and other historical family and social variables. Vital signs were recorded. Focal hyperintensities were counted by observers who were not provided any information about the subjects other than that they were either volunteers or patients. Each of the variables in the history was tested for an association with the number of focal hyperintensities seen on MR images. RESULTS. A statistically significant positive association was found between both age and the use of antihypertensive medications and the number of focal hyperintensities. Associations were also found between the number of focal hyperintensities and diastolic and systolic blood pressures at the time of MR imaging, but these associations did not reach statistical significance. No other variables in the medical, surgical, or social histories were found to be significantly related to the number of focal hyperintensities. CONCLUSION. Age and the use of antihypertensive medications were the only significant risk factors identified in respect to focal hyperintensities of the cerebral white matter.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
K. L. Salzman, A. G. Osborn, P. House, J. R. Jinkins, A. Ditchfield, J. A. Cooper, and R. O. Weller
Giant Tumefactive Perivascular Spaces
AJNR Am. J. Neuroradiol., February 1, 2005; 26(2): 298 - 305.
[Abstract] [Full Text] [PDF]

Home page
 AJGPHome page
I. A. Cook, A. F. Leuchter, M. L. Morgan, J. J. Dunkin, E. Witte, S. David, L. Mickes, R. O'Hara, S. Simon, R. Lufkin, et al.
Longitudinal Progression of Subclinical Structural Brain Disease in Normal Aging
Am J Geriatr Psychiatry, April 1, 2004; 12(2): 190 - 200.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
M. Rovaris, G. Iannucci, M. Cercignani, M. P. Sormani, N. De Stefano, S. Gerevini, G. Comi, and M. Filippi
Age-related Changes in Conventional, Magnetization Transfer, and Diffusion-Tensor MR Imaging Findings: Study with Whole-Brain Tissue Histogram Analysis
Radiology, June 1, 2003; 227(3): 731 - 738.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
C. D. Smith, D. A. Snowdon, H. Wang, and W. R. Markesbery
White matter volumes and periventricular white matter hyperintensities in aging and dementia
Neurology, February 22, 2000; 54(4): 838 - 842.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by the American Roentgen Ray Society.