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American Journal of Roentgenology, Vol 161, 1265-1268, Copyright © 1993 by American Roentgen Ray Society

ARTICLES

Parathyroid scintigraphy with iodine-123 and 99mTc-sestamibi: imaging findings

GJ Burke, JP Wei and EF Binet
Department of Radiology, Medical College of Georgia, Augusta 30912-3910.

Subtraction scintigraphy with 99mTc-pertechnetate and 201Tl-chloride is widely used for localizing the parathyroid gland, but the sensitivity of this method averages only 55%. The sensitivity of scintigraphy is improved by using a combination of 99mTc-sestamibi and iodine-123. Parathyroid adenomas can also be localized with 99mTc-sestamibi alone by subtracting early images from late sequential images. The fast washout of 99mTc-sestamibi from the thyroid gland allows visualization of the parathyroid gland. The purpose of this essay is to illustrate the findings of abnormalities of the parathyroid glands when using a combination of 99mTc-sestamibi and iodine-123.
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T. Rink, H.-J. Schroth, L.-H. Holle, and H. Garth
Limited Sensitivity of Parathyroid Imaging with 99mTc-Sestamibi/123I Subtraction in an Endemic Goiter Area
J. Nucl. Med., September 1, 2002; 43(9): 1175 - 1180.
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