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American Journal of Roentgenology, Vol 162, 299-303, Copyright © 1994 by American Roentgen Ray Society
ARTICLES |
DB Kopans
Department of Radiology, Massachusetts General Hospital, Boston.
Science is and should be the foundation of modern medicine, but observation and experience remain key elements in day-to-day clinical care. As mammography and other breast imaging techniques have evolved, early impressions have been replaced by more rigorous scientific testing, which has led to a more thorough understanding of the breast and the anatomic and morphologic origins of the imaging observations. As is true in many reports that involve the use of a new technique, early information is observational and anecdotal and frequently lacking the all-important "denominator" for a particular observation. For a "sign" to be accepted as a reliable indicator of a process, its associations must be compared with the overall prevalence of the observation in the healthy population. Observed associations must be corroborated by objective analysis.
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D. B. Kopans Bias in the Medical Journals: A Commentary Am. J. Roentgenol., July 1, 2005; 185(1): 176 - 182. [Abstract] [Full Text] [PDF] |
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