American Journal of Roentgenology, Vol 167, 1159-1162, Copyright © 1996 by American Roentgen Ray Society

ARTICLES

Tumorous intrahepatic lymphoproliferative disorder in transplanted livers

PJ Strouse, JF Platt, IR Francis and RL Bree
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0252, USA.

OBJECTIVE: We describe the radiologic findings of lymphoproliferative disorder manifesting as an intrahepatic mass in hepatic transplant recipients. Three patients with focal intrahepatic masses due to lymphoproliferative disorder after transplantation were retrospectively identified. Clinical features and radiologic findings in these patients were reviewed in conjunction with pertinent cases from the literature. (Reports of lymphoproliferative disorder confined to the transplanted liver have been sporadic.) CONCLUSION: Factors supporting the diagnosis of tumorous intrahepatic lymphoproliferative disorder include presentation 4-12 months after transplantation; portal or periportal location; poorly defined extrahepatic periportal soft tissue; encasement or narrowing of the biliary ducts, hepatic artery, or portal vein; and serologic evidence of exposure to Epstein-Barr virus.
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