AJR Women's Imaging Online
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Melhem, E. R.
Right arrow Articles by Walker, R. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melhem, E. R.
Right arrow Articles by Walker, R. E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

American Journal of Roentgenology, Vol 171, 803-807, Copyright © 1998 by American Roentgen Ray Society

ARTICLES

Usefulness of optimized gadolinium-enhanced fast fluid-attenuated inversion recovery MR imaging in revealing lesions of the brain

ER Melhem, RJ Bert and RE Walker
Department of Radiology, Boston University Medical Center, MA 02118, USA.

OBJECTIVE: The purpose of this study was to compare the contrast enhancement of lesions of the brain revealed by gadolinium-enhanced optimized fast fluid-attenuated inversion recovery (FLAIR) MR imaging with that of lesions on gadolinium-enhanced optimized T1-weighted spin- echo MR imaging. SUBJECTS AND METHODS: Using computer simulations, we optimized the fast FLAIR parameters (TR, TEeff, and inversion time) and the T1-weighted spin-echo parameters (TR and TE) to provide maximum difference in signal intensity between enhancing lesions of the brain and white matter. Seventy-six consecutive patients referred for single- dose gadolinium-enhanced MR imaging of the brain underwent both optimized techniques, which were matched for spatial resolution, bandwidth, and number of excitations. The gadolinium-enhanced fast FLAIR and T -weighted spin-echo MR images were evaluated independently by two observers for number and size of enhancing lesions and for the degree of gray-white matter differentiation. Contrast-to-noise ratios were measured for enhancing lesions 1.0 cm or larger in diameter using 8 x 8 pixel regions of interest in the enhancing lesions and normal white matter. RESULTS: The most revealing parameters for fast FLAIR MR imaging proved to be a TR of 1500 msec, an inversion time of 683 msec, and a TEeff of 16 msec. For T1-weighted spin-echo MR imaging, the optimized parameters were a TR of 550 msec and a TE of 16 msec. In 28 patients, we saw enhancing lesions of the brain with at least one MR imaging technique. More lesions were seen on the T1-weighted spin-echo sequence (n = 141) than on the fast FLAIR sequence (n = 94) (p < .03). Gray-white matter differentiation was significantly better on the fast FLAIR sequence (p < .001). Contrast-to-noise ratios of enhancing lesions were greater on the T1-weighted spin-echo sequence (p < .001). CONCLUSION: In this study, optimized gadolinium-enhanced conventional T1-weighted spin-echo MR imaging proved superior to gadolinium-enhanced fast FLAIR MR imaging in revealing lesions of the brain.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
Y.-F. Qian, C.-L. Yu, C. Zhang, and Y.-Q. Yu
MR T1-Weighted Inversion Recovery Imaging in Detecting Brain Metastases: Could It Replace T1-Weighted Spin-Echo Imaging?
AJNR Am. J. Neuroradiol., April 1, 2008; 29(4): 701 - 704.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
N. Ercan, S. Gultekin, H. Celik, T. E. Tali, Y. A. Oner, and G. Erbas
Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery MR Imaging of Intracranial Metastases
AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 761 - 765.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
H.-K. Yoon, H.-J. Shin, and Y. W. Chang
"Ivy Sign" in Childhood Moyamoya Disease: Depiction on FLAIR and Contrast-enhanced T1-weighted MR Images
Radiology, March 21, 2002; (2002) 2232011094.
[Abstract] [Full Text]

Home page
 Am. J. Roentgenol.Home page
K. Tsuchiya, S. Katase, A. Yoshino, and J. Hachiya
FLAIR MR Imaging for Diagnosing Intracranial Meningeal Carcinomatosis
Am. J. Roentgenol., June 1, 2001; 176(6): 1585 - 1588.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. H. Herlihy, J. V. Hajnal, W. L. Curati, N. Virji, A. Oatridge, B. K. Puri, and G. M. Bydder
Reduction of CSF and Blood Flow Artifacts on FLAIR Images of the Brain with k-Space Reordered by Inversion Time at each Slice Position (KRISP)
AJNR Am. J. Neuroradiol., May 1, 2001; 22(5): 896 - 904.
[Abstract] [Full Text]

Home page
 RadiologyHome page
S. K. Singh, J. M. Agris, N. E. Leeds, and L. E. Ginsberg
Intracranial Leptomeningeal Metastases: Comparison of Depiction at FLAIR and Contrast-enhanced MR Imaging
Radiology, October 1, 2000; 217(1): 50 - 53.
[Abstract] [Full Text]

Home page
 RadiologyHome page
H.-K. Yoon, H.-J. Shin, and Y. W. Chang
"Ivy Sign" in Childhood Moyamoya Disease: Depiction on FLAIR and Contrast-enhanced T1-weighted MR Images
Radiology, May 1, 2002; 223(2): 384 - 389.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the American Roentgen Ray Society.