American Journal of Roentgenology, Vol 171, 1627-1630, Copyright © 1998 by American Roentgen Ray Society
Evaluation of maximum neointima proliferation and plaque morphology in iliac self-expanding nitinol stents with intravascular sonography
H Schwarzenberg, S Muller-Hulsbeck, CC Gluer, JC Steffens and M Heller
Department of Radiology, Christian-Albrechts-Universitat zu Kiel, Germany.
OBJECTIVE: The purpose of this study was to use intravascular sonography to
evaluate neointima formation, plaque location, and the performance of
self-expanding nitinol (Memotherm) stents in iliac arteries. SUBJECTS AND
METHODS: Seventeen patients (mean age, 64+/-9.4 years) with stenoses or
occlusions of the common (n = 12) or external (n = 5) iliac artery were
treated with 21 Memotherm stents (mean diameter +/- SD, 8.9+/-1.3 mm; mean
length, 53+/-20.9 mm). Four patients had two stents each. Intravascular
sonography was performed 13+/-6 months after stent implantation. Maximum
thickness of neointima and maximum cross-sectional plaque area were
measured. Qualitative analysis of plaque composition and lesion topography
were also assessed. RESULTS: Intravascular sonography revealed
22.1%+/-17.3% maximum percentage of restenosis, and maximum plaque area was
found to be 11.2+/-10 mm2. Only hypoechogenic in-stent lesions (soft
plaques) were found. Seven (33%) incomplete stent expansions and two (10%)
incomplete appositions of the stent to the vessel wall were revealed by
intravascular sonography. CONCLUSION: Iliac artery Memotherm stents
generally showed moderate in-stent restenosis with uniform neointima
distribution. Incomplete stent expansion was detected in one third of all
implanted stents.
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