| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 All authors: Department of Radiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, One Medical Center Dr., Lebanon, NH 03756.
OBJECTIVE. Our goal was to determine how the three-dimensional structure of hyaline cartilage affects its MR appearance and to correlate this appearance with detailed structural analysis using scanning electron microscopy and freeze-fracture sectioning techniques.
MATERIALS AND METHODS. In vitro 7-T spin-echo MR images of hyaline cartilage specimens from four patients undergoing above-knee amputations were obtained parallel and perpendicular to the main magnetic field. Specimens were imaged with low- and high-power scanning electron microscopy after freeze fracturing. The corresponding images from both techniques were analyzed with specific attention to the three-dimensional structure of the cartilage, collagen fibril orientation, and respective changes in the MR appearance.
RESULTS. Freeze fracturing of cartilage reveals a curved fracture plane. Expected changes in signal intensity predicted by the magic angle effect correlated with observed changes in signal intensity across the thickness of the sample. Changes in individual collagen fibril orientation did not correspond to MR layering.
CONCLUSION. The three-dimensional organization of collagen in cartilage has a strong influence on the MR appearance of cartilage. This influence is caused by the restriction of water mobility and the resulting magic angle effect caused by curvature of the collagen network, possibly because of the influence on proteoglycan orientation.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  G. H. Welsch, T. C. Mamisch, S. E. Domayer, R. Dorotka, F. Kutscha-Lissberg, S. Marlovits, L. M. White, and S. Trattnig Cartilage T2 Assessment at 3-T MR Imaging: In Vivo Differentiation of Normal Hyaline Cartilage from Reparative Tissue after Two Cartilage Repair Procedures--Initial Experience Radiology, April 1, 2008; 247(1): 154 - 161. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. G. Potter and L. F. Foo Magnetic Resonance Imaging of Articular Cartilage: Trauma, Degeneration, and Repair Am. J. Sports Med., April 1, 2006; 34(4): 661 - 677. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. P. Recht, D. W. Goodwin, C. S. Winalski, and L. M. White MRI of Articular Cartilage: Revisiting Current Status and Future Directions Am. J. Roentgenol., October 1, 2005; 185(4): 899 - 914. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Sugita, A. Furuta, K. Ito, N. Fujita, R. Ichinohasama, and S. Takahashi Periampullary Tumors: High-Spatial-Resolution MR Imaging and Histopathologic Findings in Ampullary Region Specimens Radiology, June 1, 2004; 231(3): 767 - 774. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Goodwin, Y. Z. Wadghiri, H. Zhu, C. J. Vinton, E. D. Smith, and J. F. Dunn Macroscopic Structure of Articular Cartilage of the Tibial Plateau: Influence of a Characteristic Matrix Architecture on MRI Appearance Am. J. Roentgenol., February 1, 2004; 182(2): 311 - 318. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Goodwin, J. F. Dunn, T. J. Mosher, H. E. Smith, and B. J. Dardzinski MR Imaging and T2 Mapping of Femoral Cartilage Am. J. Roentgenol., June 1, 2002; 178(6): 1568 - 1570. [Full Text] [PDF]
|
|
|
|
 |
|
 C. Yuan, S.-x. Zhang, N. L. Polissar, D. Echelard, G. Ortiz, J. W. Davis, E. Ellington, M. S. Ferguson, and T. S. Hatsukami Identification of Fibrous Cap Rupture With Magnetic Resonance Imaging Is Highly Associated With Recent Transient Ischemic Attack or Stroke Circulation, January 15, 2002; 105(2): 181 - 185. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. J. Mosher, H. Smith, B. J. Dardzinski, V. J. Schmithorst, and M. B. Smith MR Imaging and T2 Mapping of Femoral Cartilage: In Vivo Determination of the Magic Angle Effect Am. J. Roentgenol., September 1, 2001; 177(3): 665 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. B. Kneeland Articular Cartilage and the Magic Angle Effect Am. J. Roentgenol., September 1, 2001; 177(3): 671 - 672. [Full Text] [PDF]
|
|
|
|
|
|
I. Yamada, N. Saito, K. Takeshita, N. Yoshino, A. Tetsumura, J. Kumagai, and H. Shibuya Early Gastric Carcinoma: Evaluation with High-Spatial-Resolution MR Imaging in Vitro Radiology, July 1, 2001; 220(1): 115 - 121. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
