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AJR 2000; 174:509-515
© American Roentgen Ray Society


Predictors of Patient Response to Pulmonary Thromboendarterectomy

Colleen J. Bergin1,2, Claude Sirlin1, Reena Deutsch3, Peter Fedullo4, John Hauschildt1, Tung Huynh1, William Auger4 and Michele Brown1

1 Department of Radiology, University of California, 200 W. Arbor Dr., San Diego, CA 92103.
2 Present address: Department of Anatomy with Radiology, University of Auckland, Park Rd., Auckland, New Zealand.
3 General Clinical Research Center, University of California, San Diego, CA 92103.
4 Department of Medicine, University of California, San Diego, CA 92103.

OBJECTIVE. We sought to identify imaging features that help predict surgical success in patients undergoing thromboendarterectomy.

MATERIALS AND METHODS. Thirty-nine consecutive patients who underwent pulmonary angiography and thromboendarterectomy during 1995 and 1996 were included. Thirty-four underwent helical CT angiography. Measurements of postoperative pulmonary vascular resistance were compared with preoperative imaging features and preoperative pulmonary vascular resistance.

RESULTS. The best imaging indicators of a relatively high postoperative pulmonary vascular resistance were the extent of small vessel disease identified on CT angiograms as segments with abnormal perfusion but normal segmental arteries (p = 0.005) and the extent of central disease (p = 0.015). Combined with preoperative pulmonary vascular resistance, these features had a strong correlation with postoperative outcome (p = 0.0005). Segmental arterial disease seen on both conventional angiography and CT angiography correlated poorly with surgical outcome.

CONCLUSION. In patients with chronic thromboembolic pulmonary hypertension, CT angiographic evidence of extensive central vessel disease and limited small vessel involvement indicates a favorable surgical outcome.


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