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AJR 2001; 176:537-539
© American Roentgen Ray Society

Original Report

Effect of T1 Relaxation Time on Lesion Contrast Enhancement in FLAIR MR Imaging

A Study Using Computer-Generated Brain Maps

Elias R. Melhem1 and Ryuta Itoh1

1 Both authors: Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, The Johns Hopkins Medical Institutions, 600 N. Wolfe St., Baltimore, MD 21287-2182.

OBJECTIVE. Using computer-generated brain maps, we aimed to define T1 relaxation time thresholds above which a T2 hyperintense (compared with surrounding white matter) lesion became hypointense on fluid-attenuated inversion recovery (FLAIR) MR imaging. Thresholds were identified for FLAIR MR imaging sequences with different echo times (TEs).

CONCLUSION. Thresholds for T1 relaxation times increased as TE increased during FLAIR MR imaging sequences. Such thresholds defined the transition from hyperintense to hypointense lesions.


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