| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 All authors: Department of Radiology, A-113, Albany Medical College, 47 New Scotland Ave., Albany, NY 12208.
OBJECTIVE. This study was performed to evaluate the MR imaging appearance and clinical response of patients undergoing uterine artery embolization for the treatment of menorrhagia due to adenomyosis.
MATERIALS AND METHODS. A retrospective review of 15 patients with adenomyosis and menorrhagia who underwent uterine artery embolization was performed. The diagnosis of adenomyosis was based on established MR imaging criteria. Clinical response was assessed at a minimum of 3 months after embolization. Follow-up MR imaging was performed 6 months after embolization.
RESULTS. Of the 15 patients in this study, five had diffuse adenomyosis without evidence of uterine fibroids, one had focal adenomyosis without evidence of uterine fibroids, and the remaining nine had adenomyosis with one or more fibroids. At follow-up, 12 (92.3%) of the 13 patients reported significant improvement in presenting symptoms and quality of life. One patient continued experiencing menorrhagia, and one patient experienced amenorrhea during the 5 months of follow-up after embolization. MR imaging in nine patients, performed at a mean of 5.9 months after embolization, revealed significant reductions in median uterine volume (42%), median fibroid volume (71%), and mean—junctional-zone thickness (11 mm; 33%; p < 0.5). Six of the nine patients had subendometrial regions of decreased T2 signal intensity after embolization.
CONCLUSION. Uterine artery embolization is a promising nonsurgical alternative for patients with menorrhagia and adenomyosis. Significant improvement in presenting symptoms and in quality of life is associated with decreases in uterine size and junctional zone thickness. Larger prospective studies are needed to establish the safety and efficacy of this procedure for patients with adenomyosis.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  A. Van Langendonckt, J. Donnez, S. Defrere, G. A.J. Dunselman, and P. G. Groothuis Antiangiogenic and vascular-disrupting agents in endometriosis: pitfalls and promises Mol. Hum. Reprod., May 1, 2008; 14(5): 259 - 268. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Verma, D. Bergin, C. F. Gonsalves, D. G. Mitchell, A. S. Lev-Toaff, and L. Parker Submucosal Fibroids Becoming Endocavitary Following Uterine Artery Embolization: Risk Assessment by MRI Am. J. Roentgenol., May 1, 2008; 190(5): 1220 - 1226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Kim, S. Kim, N. K. Kim, M. H. Lee, E. H. Ahn, H. J. Kim, J. H. Cho, and S. H. Cha Long-Term Results of Uterine Artery Embolization for Symptomatic Adenomyosis Am. J. Roentgenol., January 1, 2007; 188(1): 176 - 181. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. L. Spielmann, C. Keogh, B. B. Forster, M. L. Martin, and L. S. Machan Comparison of MRI and sonography in the preliminary evaluation for fibroid embolization. Am. J. Roentgenol., December 1, 2006; 187(6): 1499 - 1504. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Kitamura, S. J. Allison, R. C. Jha, J. B. Spies, P. A. Flick, and S. M. Ascher MRI of adenomyosis: changes with uterine artery embolization. Am. J. Roentgenol., March 1, 2006; 186(3): 855 - 864. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Goldberg, J.-P. Pelage, D. Jacob, and O. L. Dref Uterine Artery Embolization for Adenomyosis: Looking at the Glass Half Full * Dr Pelage and colleagues respond: Radiology, September 1, 2005; 236(3): 1111 - 1112. [Full Text] [PDF]
|
|
|
|
 |
|
 S. Ghai, D. K. Rajan, M. S. Benjamin, M. R. Asch, and S. Ghai Uterine Artery Embolization for Leiomyomas: Pre- and Postprocedural Evaluation with US RadioGraphics, September 1, 2005; 25(5): 1159 - 1172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Pelage, D. Jacob, A. Fazel, J. Namur, A. Laurent, R. Rymer, and O. Le Dref Midterm Results of Uterine Artery Embolization for Symptomatic Adenomyosis: Initial Experience Radiology, March 1, 2005; 234(3): 948 - 953. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Tamai, K. Togashi, T. Ito, N. Morisawa, T. Fujiwara, and T. Koyama MR Imaging Findings of Adenomyosis: Correlation with Histopathologic Features and Diagnostic Pitfalls RadioGraphics, January 1, 2005; 25(1): 21 - 40. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. McLucas, R. Perrella, and R. C. Jha Adenomyosis: MRI of the Uterus Treated with Uterine Artery Embolization Am. J. Roentgenol., April 1, 2004; 182(4): 1084 - 1085. [Full Text] [PDF]
|
|
|
|
 |
|
 R. L. Worthington-Kirsch and G. P. Siskin Uterine Artery Embolization for Symptomatic Myomata J Intensive Care Med, January 1, 2004; 19(1): 13 - 21. [Abstract] [PDF]
|
|
|
|
|
|
R. C. Jha, J. Takahama, I. Imaoka, S. J. Korangy, J. B. Spies, C. Cooper, and S. M. Ascher Adenomyosis: MRI of the Uterus Treated with Uterine Artery Embolization Am. J. Roentgenol., September 1, 2003; 181(3): 851 - 856. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L.-Y. Huang, Y.-F. Cheng, C.-C. Huang, S.-Y. Chang, and F.-T. Kung Incomplete vaginal expulsion of pyoadenomyoma with sepsis and focal bladder necrosis after uterine artery embolization for symptomatic adenomyosis: Case report Hum. Reprod., January 1, 2003; 18(1): 167 - 171. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. McLucas, R. Perrella, L. Adler, G. P. Siskin, M. E. Tublin, K. Dowling, and E. G. Dolen Embolization for the Treatment of Adenomyosis Am. J. Roentgenol., April 1, 2002; 178(4): 1028 - 1029. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
