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Fast Three-Point Dixon MR Imaging Using Low-Resolution Images for Phase Correction

A Comparison with Chemical Shift Selective Fat Suppression for Pediatric Musculoskeletal Imaging

¹ Department of Radiology, Children's Hospital and Harvard Medical School, 330 Longwood Ave., Boston, MA 02115.
² Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St., Boston, MA 02115.
³ Edward B. Singleton Department of Diagnostic Imaging, Texas Children's Hospital and Baylor College of Medicine, 6621 Fannin St., Houston, TX 77030.
⁴ Department of Radiology, Children's Hospital, The Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195.
⁵ Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit St., Boston, MA 02114.
⁶ Department of Radiology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston TX 77030.

OBJECTIVE. The purpose of this study is to describe and to implement a new fast three-point Dixon MR imaging sequence with online image reconstruction, and to compare this sequence with conventional chemical shift selective (CHESS) suppression of fat in pediatric musculoskeletal imaging.

SUBJECTS AND METHODS. A three-point Dixon technique using a fast spin-echo sequence with a new phase-correction algorithm providing online image reconstruction was implemented on a 1.5-T scanner. Twelve pediatric patients and young adults were imaged with both the new three-point Dixon and conventional CHESS sequences. Three radiologists un-aware of imaging parameters and clinical information independently scored the homogeneity of fat suppression and conspicuity of abnormality using a four-point system. An additional comparison between the two techniques was made using a phantom.

RESULTS. The three-point Dixon method showed superior fat suppression and lesion conspicuity (p < 0.001), particularly in the hands and feet, where CHESS is prone to inconsistent fat suppression. The phantom study showed no significant difference in the ratio of suppressed fat signal to background noise and more homogeneous fat suppression using the three-point Dixon method.

CONCLUSION. Compared with CHESS, the new fast three-point Dixon sequence with online image reconstruction provides superior fat suppression and lesion conspicuity and can be routinely used in pediatric musculoskeletal imaging.

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