HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Omary, R. A. Articles by Grist, T. M. Search for Related Content PubMed PubMed Citation Articles by Omary, R. A. Articles by Grist, T. M. Social Bookmarking                      What's this?

Comparison of Intraarterial and IV Gadolinium-Enhanced MR Angiography with Digital Subtraction Angiography for the Detection of Renal Artery Stenosis in Pigs

¹ Department of Radiology, Northwestern University Medical School, 676 N. St. Claire St., Ste. 800, Chicago, IL 60611.
² Department of Radiology, University of Wisconsin-Madison Medical School, 600 Highland Ave., Madison, WI 53792.
³ Department of Medical Physics, University of Wisconsin-Madison Medical School, Madison, WI 53792.

OBJECTIVE. Catheter-based intraarterial injections of gadolinium are useful during MR imaging—guided endovascular procedures to generate rapid vascular road maps. Using an animal model of renal artery stenosis, we tested the hypothesis that intraarterial gadolinium-enhanced MR angiography is as accurate as IV gadolinium-enhanced MR angiography and digital subtraction angiography (DSA). We also tested the hypothesis that intraarterial MR angiography uses less gadolinium than IV MR angiography.

MATERIALS AND METHODS. We induced bilateral renal artery stenosis in five pigs. All pigs underwent comparative imaging with DSA, IV MR angiography, and aortic catheter-directed intraarterial MR angiography. For IV and intraarterial MR angiography, we used the same three-dimensional acquisition. We assessed differences in quantitative stenosis measurements among DSA, IV MR angiography, and intraarterial MR angiography using the Wilcoxon's signed rank test.

RESULTS. Mean stenosis measurements (±SD) were as follows: DSA, 58% ± 12%; IV MR angiography, 63% ± 9.3%; and intraarterial MR angiography, 64% ± 11%. There were no statistically significant differences in accuracy between DSA and IV MR angiography (p = 0.06), DSA and intraarterial MR angiography (p = 0.16), or IV and intraarterial MR angiography (p = 0.70). Intraarterial MR angiography used a mean gadolinium dose of 5.6 mL, compared with 9 mL for IV MR angiography.

CONCLUSION. In swine, IV and intraarterial MR angiography have a similar accuracy for detecting renal artery stenosis. Intraarterial MR angiography uses smaller doses of injected gadolinium.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				F. Poschenrieder, O. W. Hamer, T. Herold, T. Schleicher, I. Borisch, S. Feuerbach, and N. Zorger Diagnostic Accuracy of Intraarterial and IV MR Angiography for the Detection of Stenoses of the Infrainguinal Arteries Am. J. Roentgenol., January 1, 2009; 192(1): 117 - 121. [Abstract] [Full Text] [PDF]

				H. Ersoy and F. J. Rybicki MR Angiography of the Lower Extremities Am. J. Roentgenol., June 1, 2008; 190(6): 1675 - 1684. [Abstract] [Full Text] [PDF]

				J. K. Park, T. K. Rhee, T. A. Cashen, W. Shin, B. E. Schirf, J. A. Gehl, A. C. Larson, P. V. Prasad, D. Li, T. J. Carroll, et al. Renal Artery Stenosis in Swine: Feasibility of MR Assessment of Renal Function during Percutaneous Transluminal Angioplasty Radiology, July 1, 2007; 244(1): 144 - 150. [Abstract] [Full Text] [PDF]

				R. W. Huegli, M. Aschwanden, G. Bongartz, K. Jaeger, H.-G. Heidecker, C. Thalhammer, A.-C. Schulte, C. Hashagen, A. L. Jacob, and D. Bilecen Intraarterial MR Angiography and DSA in Patients with Peripheral Arterial Occlusive Disease: Prospective Comparison Radiology, June 1, 2006; 239(3): 901 - 908. [Abstract] [Full Text] [PDF]

				R. A. Omary, J. A. Gehl, B. E. Schirf, J. D. Green, B. Lu, F. S. Pereles, J. Huang, A. C. Larson, and D. Li MR Imaging- versus Conventional X-ray Fluoroscopy-guided Renal Angioplasty in Swine: Prospective Randomized Comparison Radiology, February 1, 2006; 238(2): 489 - 496. [Abstract] [Full Text] [PDF]

				N. Zorger, M. Volk, O. W. Hamer, M. Lenhart, J. Seitz, B. Butz, and C. Paetzel Intraarterial Gadolinium-Enhanced MR Angiography in Humans for the Detection of Infrainguinal Arterial Stenoses Before and After Percutaneous Angioplasty Am. J. Roentgenol., October 1, 2005; 185(4): 867 - 872. [Abstract] [Full Text] [PDF]

				A.-C. Schulte, G. Bongartz, R. Huegli, M. Aschwanden, K. A. Jaeger, W. Ostheim-Dzerowycz, A. L. Jacob, and D. Bilecen Intraarterial Versus IV Gadolinium Injections for MR Angiography: Quantitative and Qualitative Assessment of the Infrainguinal Arteries Am. J. Roentgenol., September 1, 2005; 185(3): 735 - 740. [Abstract] [Full Text] [PDF]

				P. Perreault, M. A. Edelman, R. A. Baum, E. K. Yucel, R. M. Weisskoff, K. Shamsi, and E. R. Mohler III MR Angiography with Gadofosveset Trisodium for Peripheral Vascular Disease: Phase II Trial Radiology, December 1, 2003; 229(3): 811 - 820. [Abstract] [Full Text] [PDF]