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AJR 2002; 178:755-761
© American Roentgen Ray Society

Thick-Section Half-Fourier Rapid Acquisition with Relaxation Enhancement MR Cholangiopancreatography

Effects of IV Administration of Gadolinium Chelate

Masayuki Kanematsu1, Masayuki Matsuo1, Yoshimune Shiratori2, Hiroshi Kondo1, Hiroaki Hoshi1, Ichiro Yasuda2 and Hisataka Moriwaki2

1 Department of Radiology, Gifu University School of Medicine, 40 Tsukasamachi, Gifu, Japan, 500-8705.
2 First Department of Internal Medicine, Gifu University School of Medicine, Gifu, Japan, 500-8705.

OBJECTIVE. Our purpose was to investigate the effects of IV administration of gadolinium chelate on thick-section MR cholangiopancreatography performed with half-Fourier rapid acquisition with relaxation enhancement sequence.

SUBJECTS AND METHODS. Unenhanced and enhanced MR cholangiopancreatograms obtained in 50 consecutive patients were quantitatively analyzed with region-of-interest measurements and were qualitatively evaluated by three independent radiologists unaware the patient information. A phantom study was performed to verify the effects.

RESULTS. The mean contrast-to-noise ratios of the gallbladder, common bile duct, and main pancreatic duct significantly increased after gadolinium chelate administration (p < 0.005). The mean depiction score of the main pancreatic duct increased significantly with one radiologist (p < 0.05) and marginally with another (p < 0.06), and the mean depiction scores of the background structures and renal pelvis significantly decreased with all three radiologists (p < 0.001). The phantom study showed the results, indicating that T2- and T2*-shortening effects of gadolinium chelate caused the effects in vivo.

CONCLUSION. IV administration of gadolinium chelate improves the depiction of pancreaticobiliary ducts in some selected patients, while decreasing the depiction in others with less frequency. There may be a value of enhanced MR cholangiopancreatography when unenhanced MR cholangiopancreatography is not sufficient.


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Copyright © 2002 by the American Roentgen Ray Society.