| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Radiology, Samsung Medical Center, 50 Ilwon-dong, Kangnam-ku,
Seoul, Korea 135-710.
2 Biostatistics Unit, Samsung Biomedical Research Institute, Sungkyunkwan
University School of Medicine, Seoul 135-710, Korea.
OBJECTIVE. The purpose of our study was to determine the value of adding delayed phase imaging to dual-phase helical CT for the detection of hepatocellular carcinoma.
SUBJECTS AND METHODS. One hundred thirteen patients with 131 hepatocellular carcinomas underwent triple-phase helical CT. The diagnosis was established by pathologic examination after surgical resection in all patients. For triple-phase helical CT, hepatic arterial, portal venous, and delayed phase scanning began 30, 60, and 180 sec, respectively, after the injection of 120 mL of iodinated contrast material. Dual-phase helical CT excluding delayed phase and triple-phase helical CT images were reviewed independently by three radiologists on a segment-by-segment basis. Diagnostic accuracy was assessed using receiver operating characteristic analysis in 330 resected segments. Sensitivities and specificities were calculated. The value of the delayed phase images in the characterization of hepatocellular carcinoma was also assessed.
RESULTS. The diagnostic accuracy of triple-phase helical CT including delayed phase (area under the curve [Az], 0.973) was significantly higher than that of dual-phase helical CT (Az, 0.954). The mean sensitivity of triple-phase CT (89%) was also significantly higher than that of dual-phase CT (86%). The mean specificities of triple-phase CT (99%) and dual-phase CT (99%) were equal. Delayed phase images were helpful in the characterization of hepatocellular carcinoma in 14% of patients.
CONCLUSION. The addition of delayed phase imaging to dual-phase helical CT is valuable for the detection and characterization of hepatocellular carcinoma.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  Y K KIM, C S KIM, and Y M HAN Detection of small hepatocellular carcinoma: comparison of conventional gadolinium-enhanced MRI with gadolinium-enhanced MRI after the administration of ferucarbotran Br. J. Radiol., June 1, 2009; 82(978): 468 - 484. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Willatt, H. K. Hussain, S. Adusumilli, and J. A. Marrero MR Imaging of Hepatocellular Carcinoma in the Cirrhotic Liver: Challenges and Controversies Radiology, May 1, 2008; 247(2): 311 - 330. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. H. Kim, J. M. Lee, Y. J. Kim, J. Y. Choi, G. H. Kim, H. Y. Lee, and B. I. Choi Detection of Hepatocellular Carcinoma on CT in Liver Transplant Candidates: Comparison of PACS Tile and Multisynchronized Stack Modes Am. J. Roentgenol., May 1, 2007; 188(5): 1337 - 1342. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Monzawa, T. Ichikawa, H. Nakajima, Y. Kitanaka, K. Omata, and T. Araki Dynamic CT for Detecting Small Hepatocellular Carcinoma: Usefulness of Delayed Phase Imaging Am. J. Roentgenol., January 1, 2007; 188(1): 147 - 153. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C-S Li, R-C Chen, H-Y Tu, L-S Shih, T-A Zhang, J-M Lii, W-T Chen, S-J Duh, and L-C Chiang Imaging well-differentiated hepatocellular carcinoma with dynamic triple-phase helical computed tomography Br. J. Radiol., August 1, 2006; 79(944): 659 - 665. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-J. Kim, J. Y. Choi, J. S. Lim, J. Y. Kim, J. H. Kim, Y. T. Oh, E. H. Yoo, J. J. Chung, and K. W. Kim Optimal scan window for detection of hypervascular hepatocellular carcinomas during MDCT examination. Am. J. Roentgenol., July 1, 2006; 187(1): 198 - 206. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. R. Wilson and P. N. Burns An Algorithm for the Diagnosis of Focal Liver Masses Using Microbubble Contrast-Enhanced Pulse-Inversion Sonography. Am. J. Roentgenol., May 1, 2006; 186(5): 1401 - 1412. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Iannaccone, A. Laghi, C. Catalano, P. Rossi, F. Mangiapane, T. Murakami, M. Hori, F. Piacentini, I. Nofroni, and R. Passariello Hepatocellular Carcinoma: Role of Unenhanced and Delayed Phase Multi-Detector Row Helical CT in Patients with Cirrhosis Radiology, February 1, 2005; 234(2): 460 - 467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Giorgio, G. Ferraioli, L. Tarantino, G. de Stefano, V. Scala, F. Scarano, C. Coppola, and L. Del Viscovo Contrast-Enhanced Sonographic Appearance of Hepatocellular Carcinoma in Patients with Cirrhosis: Comparison with Contrast-Enhanced Helical CT Appearance Am. J. Roentgenol., November 1, 2004; 183(5): 1319 - 1326. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Furuta, K. Ito, T. Fujita, S. Koike, A. Shimizu, and N. Matsunaga Hepatic Enhancement in Multiphasic Contrast-Enhanced MDCT: Comparison of High- and Low-Iodine-Concentration Contrast Medium in Same Patients with Chronic Liver Disease Am. J. Roentgenol., July 1, 2004; 183(1): 157 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. K. Hussain, I. Syed, H. V. Nghiem, T. D. Johnson, R. C. Carlos, W. J. Weadock, and I. R. Francis T2-weighted MR Imaging in the Assessment of Cirrhotic Liver Radiology, March 1, 2004; 230(3): 637 - 644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. E. Steingruber, A. Mallouhi, B. V. Czermak, P. Waldenberger, E. Gassner, F. Offner, A. Chemelli, A. Koenigsrainer, W. Vogel, and W. R. Jaschke Pretransplantation Evaluation of the Cirrhotic Liver with Explantation Correlation: Accuracy of CT Arterioportography and Digital Subtraction Hepatic Angiography in Revealing Hepatocellular Carcinoma Am. J. Roentgenol., July 1, 2003; 181(1): 99 - 108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Erbay, V. Raptopoulos, E. A. Pomfret, I. R. Kamel, and J. B. Kruskal Living Donor Liver Transplantation in Adults: Vascular Variants Important in Surgical Planning for Donors and Recipients Am. J. Roentgenol., July 1, 2003; 181(1): 109 - 114. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
