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AJR 2002; 179:1059-1062
© American Roentgen Ray Society


Original Report

Cystic Changes in Hepatic Metastases from Gastrointestinal Stromal Tumors (GISTs) Treated with Gleevec (Imatinib Mesylate)

Michael Y. M. Chen1, Robert E. Bechtold1 and Paul D. Savage2

1 Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157-1088.
2 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1088.

OBJECTIVE. The purpose of this article is to illustrate the CT findings in patients with hepatic metastases from a gastrointestinal stromal tumor who were treated with STI-571.

CONCLUSION. Hepatic metastases from gastrointestinal stromal tumors that respond to treatment with STI-571 can appear as near-cystic components with well-defined borders on contrast-enhanced CT. Most metastases became smaller. These metastases resemble simple cysts, but density measurements may differentiate them from one another.


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