| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 All authors: Department of Radiology, University of Wisconsin Hospital & Clinics, 600 Highland Ave., Madison, WI 53792-3252.
OBJECTIVE. The purpose of this study was to compare hepatic tumor conspicuity on CT after injection of either 150 mL of contrast material or 100 mL of contrast material plus a 50-mL saline chaser.
SUBJECTS AND METHODS. We evaluated 86 hypoattenuating liver metastases in 26 patients. Patients underwent CT in two sessions separated by a mean of 85 days: one time with 150 mL of contrast material and the other time with 100 mL of contrast material followed by a 50-mL saline chaser. The order of the sessions was randomized. Contrast material was administered via power injector and matched for injection rate and delay time. Attenuation values were obtained from normal liver tissue and metastases and from the spleen, kidney, aorta, and inferior vena cava.
RESULTS. The 150 mL dose of contrast material caused slightly greater liver and tumor attenuation than 100 mL of contrast material with a chaser (mean hepatic attenuation, 95.6 vs 89.8 H, respectively; p < 0.03, paired t test; mean tumor attenuation, 53.2 vs 49.1 H, respectively; r = 0.71, p = 0.09). The difference in conspicuity of liver lesions was slightly greater with 150 mL than with 100 mL with a chaser (46.8 H vs 44.2 H; r = 0.46, p = 0.08, paired t test), but was of doubtful clinical significance (2.6 H). Kidney, spleen, and vascular structures enhanced more with 150 mL than with 100 mL and a chaser.
CONCLUSION. Using 100 mL of contrast material and a saline chaser did not result in a meaningful difference in liver parenchyma attenuation or lesion conspicuity compared with using 150 mL of contrast medium alone. Routine use of a chaser for abdominal CT may yield cost savings and a decreased risk of contrast nephropathy.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  D. J. Kim, T. H. Kim, S. J. Kim, D. P. Kim, C. S. Oh, Y. H. Ryu, Y. J. Kim, and B. W. Choi Saline Flush Effect for Enhancement of Aorta and Coronary Arteries at Multidetector CT Coronary Angiography Radiology, January 1, 2008; 246(1): 110 - 115. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. S. Boss, R. V. Olmos, M. Sinaasappel, J. H. Beijnen, and J. H. M. Schellens Application of PET/CT in the Development of Novel Anticancer Drugs Oncologist, January 1, 2008; 13(1): 25 - 38. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. M. Ho, R. C. Nelson, and D. M. DeLong Determining Contrast Medium Dose and Rate on Basis of Lean Body Weight: Does This Strategy Improve Patient-to-Patient Uniformity of Hepatic Enhancement during Multi-Detector Row CT? Radiology, May 1, 2007; 243(2): 431 - 437. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F Tatsugami, M Matsuki, Y Inada, G Nakai, M Tanikake, S Yoshikawa, and I Narabayashi Usefulness of saline pushing in reduction of contrast material dose in abdominal CT: evaluation of time-density curve for the aorta, portal vein and liver Br. J. Radiol., April 1, 2007; 80(952): 231 - 234. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. H. Lee, J. M. Goo, H. J. Lee, K. G. Kim, J.-G. Im, and K. T. Bae Determination of Optimal Timing Window for Pulmonary Artery MDCT Angiography Am. J. Roentgenol., February 1, 2007; 188(2): 313 - 317. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Orlandini, S. Boini, S. Iochum-Duchamps, T. Batch, X. Zhu, and A. Blum Assessment of the use of a saline chaser to reduce the volume of contrast medium in abdominal CT. Am. J. Roentgenol., August 1, 2006; 187(2): 511 - 515. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Awai, A. Hatcho, Y. Nakayama, S. Kusunoki, D. Liu, M. Hatemura, Y. Funama, M. Denbo, N. Sato, and Y. Yamashita Simulation of Aortic Peak Enhancement on MDCT Using a Contrast Material Flow Phantom: Feasibility Study Am. J. Roentgenol., February 1, 2006; 186(2): 379 - 385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. J. Jeong, K. S. Lee, S. Y. Jeong, M. J. Chung, S. S. Shim, H. Kim, O J. Kwon, and S. Kim Solitary Pulmonary Nodule: Characterization with Combined Wash-in and Washout Features at Dynamic Multi-Detector Row CT Radiology, November 1, 2005; 237(2): 675 - 683. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Awai, M. Inoue, Y. Yagyu, M. Watanabe, T. Sano, S. Nin, R. Koike, Y. Nishimura, and Y. Yamashita Moderate versus High Concentration of Contrast Material for Aortic and Hepatic Enhancement and Tumor-to-Liver Contrast at Multi-Detector Row CT Radiology, December 1, 2004; 233(3): 682 - 688. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Beyer, G. Antoch, S. Muller, T. Egelhof, L. S. Freudenberg, J. Debatin, and A. Bockisch Acquisition Protocol Considerations for Combined PET/CT Imaging J. Nucl. Med., January 1, 2004; 45(90010): 25S - 35. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
