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Hepatic Subcapsular Steatosis in Response to Intraperitoneal Insulin Delivery: CT Findings and Prevalence

¹ Department of Medical Imaging, University Health Network and Mount Sinai Hospitals, 200 Elizabeth St., Toronto, Ontario M4G 2C4, Canada.
² Department of Medical Imaging, 3-964, Princess Margaret Hospital, University Health Network, 610 University Ave., Toronto, Ontario M5G 2M9, Canada.
³ Department of Internal Medicine, University Health Network and Mount Sinai Hospitals, Toronto, Ontario M4G 2C4, Canada.
⁴ Department of Laboratory Medicine and Pathobiology, University Health Network and Mount Sinai Hospitals, Toronto, Ontario M4G 2C4, Canada.

OBJECTIVE. The aim of this study was to investigate the CT findings and prevalence of hepatic subcapsular steatosis in patients undergoing peritoneal dialysis with intraperitoneal insulin delivery.

CONCLUSION. Hepatic subcapsular steatosis appeared as subcapsular nodules and often rindlike areas of low attenuation in seven (18%) of 39 patients who received intraperitoneal insulin with their peritoneal dialysate. Cessation of intraperitoneal insulin therapy led to reversal of the steatosis in three patients.

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