HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Akira, M. Articles by Sakatani, M. Search for Related Content PubMed PubMed Citation Articles by Akira, M. Articles by Sakatani, M. Social Bookmarking                      What's this?

High-Resolution CT of Asbestosis and Idiopathic Pulmonary Fibrosis

¹ Department of Radiology, National Kinki Chuo Hospital for Chest Disease, 1180 Nagasone-cho, Sakai City, Osaka 591-8555, Japan.
² Department of Pathology, National Kinki Chuo Hospital for Chest Disease, Osaka 591-8555, Japan.
³ Department of Internal Medicine, National Kinki Chuo Hospital for Chest Disease, Osaka 591-8555, Japan.

OBJECTIVE. We studied high-resolution CT of asbestosis and idiopathic pulmonary fibrosis to determine whether differences—other than the frequency of associated pleural changes—could be discerned between the two diseases.

MATERIALS AND METHODS. High-resolution CT scans of 80 patients with asbestosis and 80 patients with idiopathic pulmonary fibrosis were retrospectively reviewed. Two chest radiologists assessed the type and distribution of parenchymal and pleural abnormalities on high-resolution CT.

RESULTS. Subpleural dotlike or branching opacities (65/80), subpleural curvilinear lines (55/80), mosaic perfusion (39/80), and parenchymal bands (38/80) were more common in patients with asbestosis (p < 0.0001). Visible intralobular bronchioles (62/80), bronchiolectasis within fibrotic consolidations (47/80), and honeycombing (61/80) were more common in patients with idiopathic pulmonary fibrosis (p < 0.0001). The frequencies of interlobular septal thickening, ground-glass opacities, fibrotic consolidation, and emphysema were similar in both groups. Parenchymal bands and fibrotic consolidation were more commonly seen (p < 0. 05) in patients with asbestosis associated with pleural disease (n = 66) than in patients with asbestosis without pleural disease (n = 14). Also, statistically significant differences were noted between high-resolution CT findings of patients with asbestosis without pleural disease and those of patients with idiopathic pulmonary fibrosis, except for parenchymal bands.

CONCLUSION. Specific combinations of high-resolution CT findings strongly suggest either asbestosis or idiopathic pulmonary fibrosis. We found that CT findings that might have represented bronchiolar obstruction in the subpleural region were more prominent in patients with asbestosis than in those with idiopathic pulmonary fibrosis, whereas bronchiolar dilatation was more prominent in patients with idiopathic pulmonary fibrosis than in those with asbestosis.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				D. M. Hansell, A. A. Bankier, H. MacMahon, T. C. McLoud, N. L. Muller, and J. Remy Fleischner Society: Glossary of Terms for Thoracic Imaging Radiology, March 1, 2008; 246(3): 697 - 722. [Abstract] [Full Text] [PDF]

				S. Misumi and D. A. Lynch Idiopathic pulmonary fibrosis/usual interstitial pneumonia: imaging diagnosis, spectrum of abnormalities, and temporal progression. Proceedings of the ATS, January 1, 2006; 3(4): 307 - 314. [Abstract] [Full Text] [PDF]