| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Diagnostic Radiology, Chinese University of Hong Kong, Prince of
Wales Hospital, Shatin, NT, Hong Kong SAR, China.
2 Present address: Department of Diagnostic Radiology, University of Texas M. D.
Anderson Cancer Center, Unit 57, 1515 Holcombe Blvd., Houston, TX 77030.
3 Department of Anatomical and Cellular Pathology, Prince of Wales Hospital,
Shatin, NT, Hong Kong SAR, China.
OBJECTIVE. The purpose of this study was to describe the features of symptomatic ductal carcinoma in situ (DCIS) of the breast shown on high-resolution sonography and to correlate them with findings from mammography and histopathology to evaluate the prognostic ability of sonographic findings.
MATERIALS AND METHODS. We retrospectively reviewed mammographic and sonographic images of 60 DCIS lesions from 55 symptomatic women. Images were reviewed by a radiologist who knew that the patients had DCIS but had no other information regarding pathology. Lesions were evaluated pathologically and classified using the Van Nuys classification system. Statistical comparisons were made using Fisher's exact test.
RESULTS. Of the 60 lesions, 33 were classified as Van Nuys group 1, 19 as Van Nuys group 2, and eight as Van Nuys group 3. Six (10%) of the 60 lesions were not visible on sonography, and 12 lesions (20%) were not visible on mammography. Sonography revealed a mass in 43 cases (72%), ductal changes in 14 cases (23%), and architectural distortion in four cases (7%). Eight lesions had more than one of these features. A sonographically visualized, irregularly shaped mass with indistinct or angular margins and no posterior acoustic shadowing or enhancement was associated with a high Van Nuys classification (p < 0.05). Microcalcifications were visible on sonography in 13 (22%) of the 60 lesions or on mammography in 25 lesions (42%). Both findings were associated with a high Van Nuys classification (p < 0.05).
CONCLUSION. Although sonography can reveal microcalcifications within masses, it is unreliable in depicting and characterizing the morphology and extent of microcalcifications, particularly when they are in isolation. Therefore, sonography should not be used to replace mammography but instead as an adjunctive tool to increase the sensitivity of mammography in breast diagnosis.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  H. J. Shin, H. H. Kim, S. M. Kim, G. Y. Kwon, G. Gong, and O. K. Cho Screening-Detected and Symptomatic Ductal Carcinoma in Situ: Differences in the Sonographic and Pathologic Features Am. J. Roentgenol., February 1, 2008; 190(2): 516 - 525. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G M Tse, P-H Tan, A L M Pang, A P Y Tang, and H S Cheung Calcification in breast lesions: pathologists' perspective J. Clin. Pathol., February 1, 2008; 61(2): 145 - 151. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. E. Dogan, K. Ceyhan, S. Tukel, S. Saylisoy, and G. J. Whitman Ductal Dilatation as the Manifesting Sign of Invasive Ductal Carcinoma J. Ultrasound Med., October 1, 2005; 24(10): 1413 - 1417. [Full Text] [PDF]
|
|
|
|
 |
|
 W. A. Berg, L. Gutierrez, M. S. NessAiver, W. B. Carter, M. Bhargavan, R. S. Lewis, and O. B. Ioffe Diagnostic Accuracy of Mammography, Clinical Examination, US, and MR Imaging in Preoperative Assessment of Breast Cancer Radiology, December 1, 2004; 233(3): 830 - 849. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
