AJR F and L Medical Products: Radiation Protection & More
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Williams, A.
Right arrow Articles by Burstein, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Williams, A.
Right arrow Articles by Burstein, D.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?
AJR 2004; 182:167-172
© American Roentgen Ray Society


Original Report

Glycosaminoglycan Distribution in Cartilage as Determined by Delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC): Potential Clinical Applications

Ashley Williams1, Amy Gillis1, Charles McKenzie1, Bruce Po1, Leena Sharma2, Lyle Micheli3, Brian McKeon4 and Deborah Burstein1

1 Department of Radiology, Beth Israel Deaconess Medical Center, 4 Blackfan Cir., Rm. 147, Boston, MA 02115.
2 Division of Rheumatology, Northwestern University Medical School, 300 E Superior St., Tarry 3-713, Chicago, IL 60611.
3 Division of Sports Medicine, Children's Hospital Boston, 319 Longwood Ave., Sixth Floor, Boston, MA 02115.
4 Department of Orthopedic Surgery, New England Baptist Hospital, ProSports Orthopedics, 840 Winter St., Waltham, MA 02451.

OBJECTIVE. We sought to describe a range of in vivo observations of glycosaminoglycan distribution in knee cartilage using the delayed gadolinium-enhanced MRI of cartilage technique.

CONCLUSION. The index of glycosaminoglycan distribution, T1Gd, can exceed 500 msec (denoting high glycosaminoglycan) or can be less than 300 msec, with focal areas as low as 240 msec. Compartmental differences, as well as focal defects within the knee, were observed in patients who had sustained injuries to the ligaments and menisci of the knee or who had chronic osteoarthritis. Overall, these results suggest the need for further research into the biochemical changes seen during disease progression and the effects of therapeutic interventions.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
RadiologyHome page
G. Andreisek, L. M. White, Y. Yang, E. Robinson, H.-L. M. Cheng, and M. S. Sussman
Delayed Gadolinium-enhanced MR Imaging of Articular Cartilage: Three-dimensional T1 Mapping with Variable Flip Angles and B1 Correction
Radiology, September 1, 2009; 252(3): 865 - 873.
[Abstract] [Full Text] [PDF]


Home page
The Journal of RheumatologyHome page
A. ANANDACOOMARASAMY, B. M. GIUFFRE, S. LEIBMAN, I. D. CATERSON, G. S. SMITH, M. FRANSEN, P. N. SAMBROOK, and L. M. MARCH
Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage: Clinical Associations in Obese Adults
J Rheumatol, May 1, 2009; 36(5): 1056 - 1062.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Roentgenol.Home page
K. Pinker, P. Szomolanyi, G. C. Welsch, T. C. Mamisch, S. Marlovits, A. Stadlbauer, and S. Trattnig
Longitudinal Evaluation of Cartilage Composition of Matrix-Associated Autologous Chondrocyte Transplants with 3-T Delayed Gadolinium-Enhanced MRI of Cartilage
Am. J. Roentgenol., November 1, 2008; 191(5): 1391 - 1396.
[Abstract] [Full Text] [PDF]


Home page
RadiologyHome page
S. R. Duc, C. W. A. Pfirrmann, M. R. Schmid, M. Zanetti, P. P. Koch, F. Kalberer, and J. Hodler
Articular Cartilage Defects Detected with 3D Water-Excitation True FISP: Prospective Comparison with Sequences Commonly Used for Knee Imaging
Radiology, October 1, 2007; 245(1): 216 - 223.
[Abstract] [Full Text] [PDF]


Home page
JBJSHome page
M. K. Shindle, L. F. Foo, B. T. Kelly, A. J. Khanna, B. G. Domb, A. Farber, T. Wanich, and H. G. Potter
Magnetic Resonance Imaging of Cartilage in the Athlete: Current Techniques and Spectrum of Disease
J. Bone Joint Surg. Am., December 1, 2006; 88(suppl_4): 27 - 46.
[Full Text] [PDF]


Home page
Am J Sports MedHome page
H. G. Potter and L. F. Foo
Magnetic Resonance Imaging of Articular Cartilage: Trauma, Degeneration, and Repair
Am. J. Sports Med., April 1, 2006; 34(4): 661 - 677.
[Abstract] [Full Text] [PDF]


Home page
JBJSHome page
A. A. Young, P. Stanwell, A. Williams, J. A. Rohrsheim, D. A. Parker, B. Giuffre, and A. M. Ellis
Glycosaminoglycan Content of Knee Cartilage Following Posterior Cruciate Ligament Rupture Demonstrated by Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC) A Case Report
J. Bone Joint Surg. Am., December 1, 2005; 87(12): 2763 - 2767.
[Full Text] [PDF]


Home page
RadiologyHome page
D. Burstein, A. Williams, C. McKenzie, K. Woertler, and E. J. Rummeny
Potential for Misinterpretation of Combined T1- and T2-weighted Contrast-enhanced MR Imaging of Cartilage * Drs Woertler and Rummeny respond:
Radiology, November 1, 2004; 233(2): 619 - 622.
[Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the American Roentgen Ray Society.