HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Müller, N. L. Articles by Nicolaou, S. Search for Related Content PubMed PubMed Citation Articles by Müller, N. L. Articles by Nicolaou, S. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

High-Resolution CT Findings of Severe Acute Respiratory Syndrome at Presentation and After Admission

¹ Department of Radiology, Vancouver General Hospital, University of British Columbia, 899 W 12th Ave., Vancouver, BC V5Z 1M9, Canada.
² Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
³ Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.

OBJECTIVE. The aim of this study was to assess the high-resolution CT (HRCT) findings at presentation and after hospital admission in patients with severe acute respiratory syndrome (SARS).

MATERIALS AND METHODS. We reviewed the HRCT findings at presentation (n = 12) and after hospital admission (n = 25) of 29 patients with SARS and compared the HRCT findings with the radiographic findings. HRCT scans were obtained using 1-mm (n = 28) or 2-mm (n = 1) collimation. The radiographs and HRCT scans were reviewed independently by two observers who reached a decision by consensus.

RESULTS. All patients had abnormal findings on HRCT at presentation. Eight of these 12 patients had normal findings on radiographs. The predominant HRCT findings at presentation consisted of unilateral (n = 6) or bilateral (n = 2) ground-glass opacities or focal unilateral (n = 2) or bilateral (n = 2) areas of consolidation. All patients showed progression of disease on follow-up. The predominant HRCT findings on follow-up CT scans consisted of unilateral (n = 2) or bilateral ground-glass opacities (n = 13), unilateral (n = 2) or bilateral consolidation (n = 5), or a mixed bilateral pattern of ground-glass attenuation, consolidation, and reticulation (n = 3). Reticulation with associated architectural distortion and mild traction bronchiectasis was present in eight patients.

CONCLUSION. HRCT can show parenchymal abnormalities in patients with SARS who have normal findings on radiographs at presentation. Follow-up CT scans obtained in hospitalized patients show findings consistent with fibrosis in a small percentage of patients.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				C. Schueller-Weidekamm, E. Wassermann, H. Redl, M. Prokop, M. Zimpfer, C. Herold, P. Germann, and R. Ullrich Dynamic CT Measurement of Pulmonary Enhancement in Piglets with Experimental Acute Respiratory Distress Syndrome. Radiology, May 1, 2006; 239(2): 398 - 405. [Abstract] [Full Text] [PDF]

				P. L. Ho, P. H. Chau, P. S. F. Yip, G. C. Ooi, P. L. Khong, J. C. Ho, P. C. Wong, C. Ko, C. Yan, and K. W. Tsang A prediction rule for clinical diagnosis of severe acute respiratory syndrome Eur. Respir. J., September 1, 2005; 26(3): 474 - 479. [Abstract] [Full Text] [PDF]