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MRI of Five Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy

¹ Department of Radiology, New York Presbyterian Hospital, Columbia-Presbyterian Center, 177 Fort Washington Ave., Milstein Hospital Bldg., Rm. 3-105, New York, NY 10032.
² Department of Radiology, College of Physicians and Surgeons, Columbia University in the City of New York, New York, NY 10032.
³ Department of Neurology, College of Physicians and Surgeons, Columbia University in the City of New York, 630 W 168th St., P&S 4-443, New York, NY 10032.

OBJECTIVE. The purpose of this study was to retrospectively review MR images of the brain in five patients diagnosed with mitochondrial neurogastrointestinal encephalomyopathy.

CONCLUSION. Our research supports previously reported findings of confluent abnormal cerebral white matter in patients with mitochondrial neurogastrointestinal encephalomyopathy. In contrast to prior studies, our cohort of five patients showed that involvement of the corpus callosum as well as the capsular white matter, basal ganglia, thalami, midbrain, pons, and cerebellar white matter is not rare and does not preclude the diagnosis of mitochondrial neurogastrointestinal encephalomyopathy.

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