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AJR 2004; 183:1629-1636
© American Roentgen Ray Society

Original Report

Gastrointestinal Stromal Tumors in Patients with Neurofibromatosis: Imaging Features with Clinicopathologic Correlation

Angela D. Levy1,2, Nandini Patel1,3, Robert M. Abbott1,2,4, Nancy Dow5, Markku Miettinen6 and Leslie H. Sobin5

1 Department of Radiologic Pathology, Armed Forces Institute of Pathology, Alaska and Fern Streets, NW, Washington, DC 20306-6000.
2 Department of Radiology and Nuclear Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814-4799.
3 Present address: Department of Medical Education, Washington Hospital Center, Washington, DC 20010-2975.
4 Department of Radiology, University of Maryland School of Medicine, Baltimore, MD 21201-1544.
5 Department of Hepatic and Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
6 Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.

OBJECTIVE. The purpose of this study was to evaluate the clinical, pathologic, and imaging features of gastrointestinal stromal tumors that occur in patients with neurofibromatosis.

CONCLUSION. Gastrointestinal stromal tumors that occur in patients with neurofibromatosis commonly originate from the proximal small intestine and are often multiple. The cross-sectional imaging appearance of gastrointestinal stromal tumors that occur in patients with neurofibromatosis is similar to that of gastrointestinal stromal tumors that occur in the general population.


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A. D. Levy, N. Patel, N. Dow, R. M. Abbott, M. Miettinen, and L. H. Sobin
From the Archives of the AFIP: Abdominal Neoplasms in Patients with Neurofibromatosis Type 1: Radiologic-Pathologic Correlation
RadioGraphics, March 1, 2005; 25(2): 455 - 480.
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