HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Diallo, O. Articles by Avni, E. F. Search for Related Content PubMed PubMed Citation Articles by Diallo, O. Articles by Avni, E. F. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Type 1 Primary Hyperoxaluria in Pediatric Patients: Renal Sonographic Patterns

¹ Department of Pediatric Imaging, Queen Fabiola Children's Hospital, Av. J.J. Crocq, Brussels 1020, Belgium.
² Department of Pediatric Nephrology, Queen Fabiola Children's Hospital, Brussels 1020, Belgium.
³ Department of Medical Imaging, Erasme Hospital, University Clinics of Brussels, 808 Route de Lennik, Brussels 1070, Belgium.

OBJECTIVE. Our aim was to review the sonographic features of type I primary hyperoxaluria in children and to correlate the sonographic patterns with the clinical development of end-stage renal disease (ESRD).

MATERIALS AND METHODS. We performed a retrospective analysis of the clinical and imaging files of 13 patients with type I primary hyperoxaluria who were treated in one institution and of the sonographic patterns and the clinical follow-up reports.

RESULTS. We encountered the following two sonographic patterns: medullary nephrocalcinosis in eight patients and cortical nephrocalcinosis in five patients. The sonographic appearance of cortical nephrocalcinosis is quite specific: a hyperechoic peripheral renal cortex with acoustic shadowing behind it. Medullary nephrocalcinosis is less specific because there are many other causes of hyperechoic pyramids. All patients with medullary nephrocalcinosis developed lithiasis during the course of the disease. All patients with cortical nephrocalcinosis but only two of eight with medullary nephrocalcinosis developed ESRD.

CONCLUSION. Sonography can be used differentiate the two patterns of type 1 primary hyperoxaluria. The cortical nephrocalcinosis type carries a higher risk of developing ESRD.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				S. Aziz, P. W. Callen, F. Vincenti, and R. Hirose Rapidly Developing Nephrocalcinosis in a Patient With End-Stage Liver Disease Who Received a Domino Liver Transplant From a Patient With Known Congenital Oxalosis J. Ultrasound Med., October 1, 2005; 24(10): 1449 - 1452. [Full Text] [PDF]