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AJR 2005; 184:1293-1304
© American Roentgen Ray Society


Pictorial Essay

PET/CT in the Evaluation of Childhood Sarcomas

M. Beth McCarville1,2, Ryan Christie2, Najat C. Daw3, Sheri L. Spunt3 and Sue C. Kaste1,2,3

1 Department of Radiological Sciences, St. Jude Children's Research Hospital, 332 N Lauderdale St., Memphis, TN 38105.
2 Department of Radiology, College of Medicine, University of Tennessee, Memphis, TN.
3 Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN.

OBJECTIVE. Our objective was to review our preliminary experience with PET/CT in evaluating childhood sarcomas including rhabdomyosarcoma (n = 28), the Ewing's sarcoma family of tumors (n = 14), nonrhabdomyosarcoma soft-tissue sarcoma (n = 9), osteosarcoma (n = 8), chondrosarcoma (n = 1), and embryonal sarcoma (n = 1).

CONCLUSION. We found PET/CT useful in depicting an unknown primary rhabdomyosarcoma and detecting unsuspected and unusual metastatic sites of childhood sarcomas. It was useful in monitoring response to chemotherapy, radiation therapy, and radiofrequency ablation and aided the postoperative evaluation of tumor resection sites.


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