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Original Report |
1 Division of Cardiology, Department of Medicine, Johns Hopkins University,
Baltimore, MD.
2 Division of Rheumatology, Department of Medicine, Johns Hopkins University,
Baltimore, MD.
3 Applied Science Laboratory, GE Healthcare, Milwaukee, WI.
4 Russell H. Morgan Department of Radiology and Radiological Sciences, Johns
Hopkins University, 600 N Wolfe St., Baltimore, MD 21287.
OBJECTIVE. Delayed contrast-enhanced MRI is increasingly being used for cardiac viability imaging. Takayasu's arteritis is a rare inflammatory disorder of unknown cause that affects the aorta, its major branches, and the pulmonary artery; it is characterized by inflammation and fibrosis in the arterial wall. We report our initial experience with seven patients (six women, one man; age range, 25–62 years) with delayed (20 min) gadolinium-enhanced MRI (inversion recovery prepared gated fast gradient-echo pulse sequence) in patients with known Takayasu's arteritis.
CONCLUSION. Patients with Takayasu's arteritis (particularly those with abnormal laboratory values) have evidence of delayed hyperenhancement on delayed contrast-enhanced MRI. Thus, delayed contrast-enhanced MRI might be a useful technique to identify inflammation in arterial wall.
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